Consequently, mitochondrial dysfunction has been identified as a central contributor to the onset and progression of various cardiovascular diseases, including HF, myocardial ischemia/reperfusion (I/R) injury, and atherosclerosis
Vitamin B-12 deficiency in the elderly: current dilemmas
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Repurposing of already approved drugs has been explored, for example, disulfiram, a drug traditionally used to treat alcohol dependence, can lower cystine levels in cystinotic cells, but has side effects that limit its use in cystinosis [151, 153]
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