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The U.K.s National Institute for Biological Standards and Control states that the ideal temperature for peptides is 4C, or 39F.25 Thats about as cool as an ordinary home refrigerator

Gao Y, Kang K, Liu Y, Li N, Han Q, Liu H, Kong W, Zhang X, Huang R, Yang Z, Qi Z, Zheng J, Li M, Wang H, Li J, Liu R, Wang S, Zhang W, Zhao M, Yu K (2021) Mechanisms of renal-splenic axis involvement in acute kidney injury mediated by the 7nachr-nf-b signaling pathway

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These findings demonstrate the context-dependent nature of IFs endocrine effects and highlight the need for longitudinal studies to determine its long-term reproductive and metabolic consequences

These are mechanistic findings from lab and animal work, not confirmed human receptor pharmacology