Knockdown of CBS promotes cellular oxidative stress and lipid peroxidation, thus enhancing ferroptosis susceptibility (51)
Stabilizza i livelli di acetil-CoA e Coenzima A nei mitocondri, facendo uscire l'acetile residuo dai processi di ossidazione (responsabili della produzione di ATP), prevenendo cos l'effetto tossico di un eventuale accumulo
Preparation Condition 4 (EDTA 4 o C deproteinization): Storage temperature affects total GSH, free GSH, and GSSG, but not the ratio of free GSH to GSSG in plasma We included EDTA-treated plasma stored at 4 o C (Preparation Condition 4) as a positive control for enzymatic degradation of glutathione which may occur during sample storage
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