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The pleiotropic effects of GLP-1 receptor agonists across seven or more organ systems are not a feature that future computation will simply solve

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Genes Dev (2018) 32:60219

TNF-, NF-B, IL-1b, AP-1, and Mitogen-activated protein kinases (MAPKs) intermediates get activated after receiving the pro-inflammatory stimuli and release pro-inflammatory chemokines, MMPs, inflammatory enzymes, adhesion molecules, and angiogenic factors resulting in neo-vascularization, arthritic joint destruction and chronic inflammation

Studies have also suggests that it may help alleviate some of the complications associated with diabetes, such as nerve damage and kidney disease