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Exercise-Induced Oxidative Stress Intense or prolonged exercise generates substantial oxidative stress through increased oxygen consumption and metabolic rate, increased mitochondrial electron leakage producing reactive oxygen species, recruitment of inflammatory immune cells to exercising muscles, and mechanical stress on tissues producing oxidative damage

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Proc Natl Acad Sci USA 93:1442814433 Winterbourn CC, Metodiewa D (1994) The reaction of superoxide with reduced glutathione

doi: 10.30476/IJMS.2021.92080.2326 134 JacobLKoyanagiASmithLTanislavCKonradMvan der BeckSet al