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The carnitine supplementation and its derivatives have shown to counteract mitochondria dysfunction and the metabolic inflexibility

A recent study further demonstrated that WBP1-deficient CRC cells regained sensitivity to 5-FU following the restoration of mitochondrial function [65], reinforcing a causal link between mitochondrial homeostasis and drug responsiveness

RNA modification is a typical process regulating gene expression at the post-transcriptional level

When unregulated, that signal can feed tumor formation or interfere with cellular apoptosis (natural cell death)

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