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Indeed, we observed that several angiogenesis-related factors were upregulated in IMQ-treated mice, and that sB suppressed their expression while sCSD had significantly less of a beneficial effect

GSH level, SOD and GST activities were significantly decreased, and NO level and TF activity did not significantly change in the MTX group compared with the control group

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It may come from preclinical data, in vitro studies, or preliminary results