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This approval was based on the SURPASS clinical trial program, which demonstrated superior glycemic control compared to placebo, semaglutide 1 mg, and insulin degludec across multiple studies

If blood sugar targets are not being met effectively on one medication, the dual action of tirzepatide might provide superior glucose management

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J Clin Invest 131(12) Schith HB et al (2012) Brain insulin signaling and Alzheimers disease: current evidence and future directions