semaglutide type 1 diabetes randomized trial 2024 Use With Automated Insulin Delivery in Adults With Diabetes: Qualitative Analyses and Patient-reported Outcomes From a Controlled Effectiveness of Semaglutide and Tirzepatide

Sustaining weight loss after tirzepatide discontinuation requires comprehensive lifestyle modification and, in some cases, alternative pharmacotherapy

The starting dosage of semaglutide is 0.25 once weekly, while the tirzepatide dosage starts at 2.5 mg once weekly

Semaglutide can influence the kidneys, especially in people with existing kidney problems

It runs for 80 weeks (the longest in the program), enrolls a general obesity population without type 2 diabetes, and is designed to be the direct apples-to-apples analogue of SURMOUNT-1 (tirzepatide) and STEP-1 (semaglutide)

Noticeable changes in the face, waist, hips, and overall body composition