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As a solution, we report that C-terminally cleaved albumin can be efficiently rescued from intracellular degradation by introducing amino acid substitutions that improve FcRn binding

Oxidative stress occurs when there's an imbalance between free radicals (unstable molecules that damage cells) and antioxidants (the molecules that neutralize them)

Severe breathing difficulty, chest pain, confusion, very high fever with shaking chills, inability to keep fluids down for over 24 hours, or signs of severe dehydration all need in-person medical evaluation first

This is possibly related to the increased mitochondrial hydrogen peroxide (49)

10.1016/j.metabol.2024.156104 74 MaX.LiuB.JiangZ.RaoZ.ZhengL