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A percentage of people will not be able to tolerate the new pharmacotherapies or achieve the individualised goals and others may not have long-term access to these treatments

Medications (Prescribed if needed) H1 blockers (examples: loratadine, cetirizine, fexofenadine) help with itching, flushing, hives H2 blockers (example: famotidine) support digestion and reduce stomach-related symptoms Mast cell stabilizers (examples: cromolyn sodium, ketotifen) calm the immune system Leukotriene inhibitors (example: montelukast) help with breathing or inflammation Epinephrine auto-injector prescribed if there is a risk of severe allergic reactions Older sedating antihistamines such as diphenhydramine are avoided for long-term use

Peedicayil, J