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doi: 10.1016/j.jplph.2014.03.002 21 GimenezE.SalinasM.Manzano-AgugliaroF
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Studies in adipocyte cell culture and in rodent metabolic models have used LR3 to characterize these effects
At the cut-off value of 5.0 ng/ml, NRF2-AS demonstrated 45% sensitivity and 52% specificity, with positive and negative predictive values of 48% and 49%, respectively
The DCCT study demonstrated that intensive insulin therapy in T1D significantly reduced the risk of DPN by 64% and cardiovascular autonomic neuropathy by 45% compared with conventional treatment, with these benefits persisting for over 13 years after the trial ended [60]
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