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If your primary goal is the greatest possible fat loss and you have not achieved sufficient results with existing GLP-1 therapies, retatrutide is the more powerful option available in 2026
The researchers found that among adults who were overweight or obese who completed the 20-week run-in period with subcutaneous semaglutide, maintaining treatment with semaglutide resulted in continued weight loss over the following 48 weeks compared to switching to placebo
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