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Wang, C., Zhao, H., & Lee, Y

Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress

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Using cold medication directly from refrigeration (rather than allowing it to reach room temperature for approximately 30 minutes as recommended in the Instructions for Use), inadequate injection technique, or repeated injections in the same area can increase tissue trauma and inflammatory responses

Some temporary swelling or redness in the treated area is expected, but this does not prevent patients from continuing their usual daily routine