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Metformin use is associated with a reduced risk of mortality in patients with diabetes hospitalised for COVID-19

Hypertension 2 , 909912 (1989)

The studys primary endpoint was change in the cerebral glucose metabolic rate in the cortical regions of the brain (hippocampus, medial temporal lobe and posterior cingulate), which was not met

This therapy has gained attention for its potential to improve energy, cognitive function, and recovery

Hypoglycemia ultimately may reflect interaction between excessive insulin secretion, inadequate counterregulatory hormone levels and/or action, reduced glycogen stores, and inadequate substrate or activity within gluconeogenic pathways