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Studies have demonstrated SASs ability to induce ferroptosis in diverse tumor cells, suggesting its potential as a combinatory treatment with other cancer therapies to enhance overall treatment effectiveness ( As an excitatory neurotransmitter that binds to both excitatory neurotransmitter binding sites and Cl - dependent cysteine- and cystine-inhibited transporter sites, the Xc-system facilitates the transfer of glutamate out of and cystine in