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Quick Answer: Tirzepatide does not require a formal tapering schedule when discontinuing treatment, as there is no physiological withdrawal syndrome associated with stopping

GLP-1 drugs were originally used to treat diabetes, but are now a popular method of weight loss, even as the drugs face concerns over affordability, insurance coverage and potential side effects, as Newsday has previously reported

The FDA has approved it for treating other conditions, but healthcare providers can prescribe it off-label if it has shown promise through research and clinical use

Sodium-glucose co-transporter-2 (SGLT-2) inhibitors and cancer: a meta-analysis of randomized controlled trials

We hypothesize that semaglutide will reduce drug reward (experiment 1) and relapse-like behavior (experiment 2)