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The journals of gerontology

Patients should also be aware of other medications they are taking that may contain acetaminophen, as this can inadvertently lead to exceeding the safe daily limit

This observation, coupled with the added stability contributed by C-terminal amidation and the desire to increase the hydrophobicity of the peptide, led to the generation of a series of compounds with the structure N -acyl-Tyr-Ile-(6) amino-hexanoic amide