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Consistent with the base-case analysis, sensitivity analyses demonstrated that using GLP-1RAs versus insulin was either cost-saving or cost-effective, except for the analyses where the treatment effectiveness was estimated based on the AT scenario in the second and third sensitivity analyses, showing that a GLP-1RA versus insulin therapy was not cost-effective for averting one case of all-cause death from the payer perspective
33 Tirzepatide Tirzepatide (a dual glucose-dependent insulinotropic peptide and GLP-1 receptor agonist) safety was evaluated in a meta-regression study that established individual adverse event rates at weekly doses of 5, 10 and 15 mg
Honey and ginger were local products from south Sulawesi, Indonesia
Chronic administration of exendin-4 is unable to prevent -cell loss in mice that are lacking Irs2 [544], demonstrating the requirement of Irs2 to GLP-1-mediated -cell plasticity
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