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The authors observed that MDS carriers of the MTHFR 677CT or TT genotype had an increased risk for DS-CHD in the offspring (OR = 2.07

The translational success of rodent studies to human disease is difficult to predict, as mice and rats often fail to recapitulate key pathophysiological features of human disease and treatment responses [27, 28]

Wismann, P

However, for those requiring a more aggressive reduction in HbA1c levels, Tirzepatide may offer a more effective solution due to its dual-action mechanism targeting both GLP-1 and GIP receptors