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Description About Retatrutide Retatrutide is a synthetic 39-amino-acid peptide engineered as a triple agonist of three incretin and metabolic receptors: GLP-1R (glucagon-like peptide-1 receptor), GIPR (glucose-dependent insulinotropic polypeptide receptor), and GCGR (glucagon receptor)

It also reduced appetite and food intake , as studies soon demonstrated ( [1] )

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Blood pressure and lipid profiles that improved during treatment may trend toward baseline values, though the timeline and magnitude vary between individuals