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Phillips MCL, Deprez LM, Mortimer GMN, Murtagh DKJ, McCoy S, Mylchreest R, et al

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IGF-1 LR3's 100-fold reduced IGFBP binding eliminates the primary clearance sink, and its larger size (9.1 kDa vs 7.6 kDa) and altered charge profile slow renal clearance

10.1002/nbm.1315 112 McGregorN