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4.1 Limitations and implications for practice This meta-analysis has several limitations that should be considered when interpreting the findings

Clinically significant vitamin B 12 deficiency and megaloblastic anemia are unlikely, unless these drug therapies are prolonged for two or more years, or if in addition, the person's dietary intake is below recommended levels

Extreme deficits (800-1,000 calories below maintenance) are unnecessary and counterproductive because they increase muscle catabolism and metabolic adaptation

Used thoughtfully as part of a broader wellness plan alongside appropriate exercise, diet, weight management, and supportive care BPC-157 may help your dog move more freely, hurt less, and have a better quality of life in their senior years

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