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Future studies should further investigate this downstream antioxidant program to better clarify the involvement of glutathione metabolism in MAPKAPK2-mediated regulation of the KEAP1/Nrf2 pathway

For example, Chinese formulations such as Xiaoyaosan and Danzhi-Xiaoyao-San have demonstrated the ability to regulate gut microbiota in animal models, leading to improved depressive behaviors

Authors were contacted if not enough data was included in the original manuscript for analysis, for clarification of terms or to confirm whether the article contained data previously published by the same research group

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