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Clinicians should weigh potential risks and benefits and monitor patients closely if offlabel use is considered

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doi: 10.1046/j.1471-4159.1994.62020519.x 41 HardingSDSharmanJLFaccendaESouthanCPawsonAJIrelandSet al

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Despite being recognized as the primary allergen among shrimp-sensitized individuals, recent findings have reported sensitization rates to Pen m 1 of less than 50%, including 31% in Australian infants [44], 37% in Japanese [45], 42% in Austrian [46], 41.2% in Chinese [47], and 41% in Italian [48] shrimp-allergic populations