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For context on what people typically eat on each medication: Mounjaro (tirzepatide) Mounjaro typically reduces calorie intake by 30 to 40% in the first few months as the dose escalates

YamadaTWakabayashiMBhallaAChopraNMiyashitaHMikamiTet alCardiovascular and renal outcomes with SGLT-2 inhibitors versus GLP-1 receptor agonists in patients with type 2 diabetes mellitus and chronic kidney disease: a systematic review and network meta-analysis

Common GLP-1 side effects include nausea, constipation, and reduced appetite intensitytypically mild and temporary during dose escalation

Contact your GP promptly if you experience persistent vomiting or diarrhoea lasting more than 24 hours, severe muscle weakness, palpitations, or confusion