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CMV -Cre), together with mitochondrial metabolomics and whole-cell tracing in the presence of D 9 -TML, revealed that SLC25A45 depletion led to markedly reduced mitochondrial uptake of D 9 -labeled TML

These compounds play vital roles in maintaining redox homeostasis, protecting cells from oxidative damage and the toxicity of xenobiotic electrophiles 75,76,77