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Intermediate : 60-80 mcg per muscle group bilaterally once youve assessed tolerance and response over 4-6 weeks

Distraction of olfactory bulb-medial prefrontal cortex circuit may induce anxiety-like behavior in allergic rhinitis

10.1093/neuonc/noaa200 86 ParkE

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In clinical practice, based on clinical response or intolerance, the starting dose of medication is 10 mg/week, with increases of 5 mg every 24 weeks, up to a maximum dose of 2030 mg/week (Visser and van der Heijde 2009