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In this study, metabolic signatures were nearly identical between pre-ASD newborns and neurotypical newborns, and differential signatures were observed only in 5-year-olds, suggesting that ASD-associated metabolic signatures develop with age and the maturation of their respective gut microbiota [315]

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Chin Med.J.(Engl.) 7-5-2011;124(13):2071-2073

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A moderate deficit of 500-750 calories below maintenance typically produces steady fat loss without excessive catabolism