Zhao J, Zhang Z, Xue Y, Wang G, Cheng Y, Pan Y, et al
Am J Physiol Cell Physiol 316: C525C544, 2019
Symptoms of high estrogen include water retention, mood changes, decreased libido, and in some cases, breast tissue sensitivity or gynecomastia
J Neurosci 27:394655, PMID: 17428968 Murphy TH, Miyamoto M, Sastre A, Schnaar RL, Coyle JT (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
Signs of Facial Sagging and Loose Skin After Weight Loss Everyones face reacts differently to weight loss, but common signs of facial sagging include: Flattened cheeks and hollow temples Loose skin under the chin and jaw (also known as jowls) Folds or creases around the mouth and nose Sagging skin around the neck or under the eyes Overall loss of facial definition These changes may make you look tired or older than you feel, even after reaching your weight loss goals