first glp 1 GLP-1R in diabetes mellitus: from basic discovery to therapeutics development Generic Liraglutide Approved, Marking First

Treatment should be discontinued in patients who develop new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema, and patients should be evaluated for the possible presence of pulmonary hypertension

BMJ 372:n71 [DOI] [PMC free article] [PubMed] [Google Scholar] 18.Sterne JAC et al (2019) RoB 2: a revised tool for assessing risk of bias in randomised trials

This decline coincides with reduced healing capacity, slower tissue regeneration, and accelerated aging

However, with the introduction of GLP-1 medications, this becomes even more crucial

24 Another study reported that even within the normal range, elevated HbA1c is associated with MASLD progression