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But when histamine levels build up faster than the body can break them down, it can lead to issues such as: Chronic itching and skin irritation Digestive upset (diarrhea, vomiting, gas) Respiratory issues (sneezing, congestion) Hyperactivity or anxiety-like behaviors If youve tried changing your pets diet, eliminating allergens, or using medications without success, histamine intolerance might be the missing piece of the puzzle

McCord, a biochemist credited with inventing the Protandim compound who went on to serve as the companys lead scientific officer, gave occasional talks to LifeVantage distributors describing how components of the supplements such as plant extracts, like milk thistle or ashwagandha might regulate a biochemical pathway by switching on particular genes

These changes in the BA pool can affect body function by regulating BA receptors in the gut (Martinot et al., 2017)

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