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1 Introduction Obesity represents a complex and widespread chronic condition, ranking among the most prevalent health issues globally (1)

Severe hypoglycemia can cause confusion, loss of consciousness, seizures, and can be life-threatening

ZG wrote the article

Besides, disruption of MTR reaction leads to insufficient supply of methionine and S-adenosylmethionine (SAM), which is essential for the myelination of myelin sheath, phospholipids and neurotransmitter synthesis, for maintaining brain and nervous system function.51 Furthermore, high levels of homocysteine due to vitamin B 12 deficiency are associated with an increased risk of atherosclerotic vascular disease, and this in turn may increase the risk of cognitive impairment or dementia