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FDA-approved GLP-1 agonists like semaglutide have 2+ year safety data from clinical trials and are designed for continuous use

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Many users unknowingly eat or consume carbs too close to their dose, blunting the GH pulse

Subcutaneous and intramuscular delivery allow more of the peptide to enter circulation directly, which is why injection is the more commonly discussed route for recovery and tissue-related goals

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