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Severe or persistent vomiting lasting more than a few hours, signs of dehydration (extreme thirst, dark urine, dizziness), or allergic reactions (rash, swelling, difficulty breathing) require urgent evaluation by your prescribing physician

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Blood (10 mL) was collected from the participants in a serum tube without anticoagulant and left for 30 min at room temperature to confirm coagulation, followed by centrifugation at 2,000 g for 10 min