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Your immune system, which monitors gut bacteria constantly through toll-like receptors and other surveillance mechanisms, also responds to the new arrivals with mild inflammatory signaling

(February 2007)

The idea of simultaneously activating both the GIP and GLP-1 receptors seems appealing for treatment of T2DM since it may significantly boost insulin secretion and improve insulin sensitivity

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Warning signs include persistent fatigue despite adequate sleep, cold intolerance (especially cold hands and feet), menstrual irregularity or cessation in female subjects, hair thinning or shedding, and mood disturbances (irritability, low motivation)