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A 2026 study in The Lancet Obstetrics, Gynaecology, & Women's Health found that combining GLP-1s and hormonal therapy could result in a 35% increase in weight loss

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Robert Kushner, professor of medicine at Northwestern University Feinberg School of Medicine and a STEP-1 investigator, has noted: "The nausea patients experience on semaglutide is fundamentally a brainstem event, not a stomach problem