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Furthermore, they demonstrated clinically relevant benefits, including a reduced requirement for exogenous pulmonary surfactant (both in the number of infants needing treatment and the total dose administered) and a shortened duration of mechanical ventilation compared to the placebo group (73)
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Meanwhile, single-cell RNA sequencing (scRNA-seq) has revealed that stem-like cell populations with elevated OXPHOS activity contribute to drug resistance and metastatic potential, providing direct evidence for the cellular basis of metabolic heterogeneity in CRC [166, 167]
Azran C, Porat D, Fine-Shamir N, Hanhan N, Dahan A
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