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However, in-depth investigations into the pathology of neurodegenerative diseases from the three perspectives, despite being crucial aspects, remain limited

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Phase 1 and Phase 2 testing of full-length T4 found no dose-limiting toxicities, with adverse events mild and transient

8,15 Serum holotranscobalamin level, which is reduced in vitamin B 12 deficiency, compared favorably with homocysteine and methylmalonic acid levels as a confirmatory test in one study, but further trials are needed before its widespread use for this purpose can be recommended