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It is evident that 2D cell lines treated with RSL3 show increased levels of lipid peroxidation compared to the control but to a different extent, in line with their different sensitivity to cell death shown in the previous paragraph
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These variations in DNA methylation may provide an explanation for the increased glucose intolerance, poorer beta cell function, and differences in cardiac anatomy and physiology in adults with a history of SAM [132, 133]
10.3390/ijms10094066 56 ErbilH.SezerE.TatanB.ArcaE.KurumluZ
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