Across these CEAs, relative to insulin, the use of a GLP-1RA could be dominated or had an ICER of US$22,682 to US$90,646 per QALY gained from the payer perspective, an ICER of US$1982 to US$42,679 per QALY gained from the healthcare sector perspective, and an ICER of US$21,488 to US$28,490 per QALY gained from the societal perspective
331,332 Multiple PD-associated genes, such as LRRK2, SYNJ1, DNAJC6, and DNAJC13, regulate synaptic endocytosis, autophagy, lysosomal function, and endolysosomal trafficking, underscoring the intertwined regulation of vesicular dynamics and proteostasis in dopaminergic neurons
Rodriguez-Muela, N., Germain, F., Marino, G., Fitze, P
[DOI] [PubMed] [Google Scholar] 29.Pickart L, Thayer L, Thaler MM
not applicable to self-use protocols Lee & Burgess 2025 (PMID 40131143): n=2 healthy adults, up to 20 mg IV over 1 hour, no adverse events, no biomarker changes