10.1016/j.scienta.2015.11.047 65 HarrachB
when all GSH has been spent, NAPQI begins to bind to certain enzymes like N-10 formyltetrahydrofolate dehydrogenase and glutamate dehydrogenase, reducing their activity and killing the cells in the process
biological function 2016 Distribution of glutathione and glutathione-related enzyme systems in mitochondria and cytosol of cultured cerebellar astrocytes and granule cells.1995 One gene two localization in mitochondria and cytosol Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences 2018 Enzymes Cell signaling and Ligand transport Structural proteins REGULATION DIAGNOSTIC USE Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration 2018 The plant mitochondrial import machinery
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Alternatively, if you want a more bioavailable form, you might try liposomal glutathione
