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In a randomized double-blind, placebo-controlled, phase 3 trial of adults with overweight or obesity without type 2 diabetes, estimated mean body weight change from baseline to weak 68 was 15.1% (SE 0.5) in the oral semaglutide group and 2.4% (0.5) in the placebo group [99]

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As obesity prevalence rises alongside ocular complications, anti-obesity medications offering both metabolic and ocular benefits may reduce eye disease burden in affected populations

Research published in the journal Genome Medicine identified that GHK modulates expression of over 4,000 human genes

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