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It upregulates matrix metalloproteinases (MMPs), which are enzymes that break down old, damaged collagen and extracellular matrix components

Similarly, 12 weeks of progressive full body RT 3 times per week (3 sets of 10 reps, progression from 50%80% 1RM), in older humans lowers basal IL-6 levels, which may represent an adaptation to the exercise (Forti et al., 2014)

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Tan S-X, Fisher-Wellman KH, Fazakerley DJ, Ng Y, Pant H, Li J, et al

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This is especially crucial for patients whose metabolic flexibility has been compromised, as it helps the body efficiently utilize stored fats for long-lasting energy, rather than relying solely on rapid, easily exhausted, and lactate-producing glucose stores