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When your body doesn't get nicotine, you may feel uncomfortable (make that very uncomfortable) and crave cigarettes

The culmination of each puff is a sweet, velvety aftertaste that lingers on the palate, elevating the smoking ritual to a sensory masterpiece

These data illustrate a specific challenge in studying the potential effects and harms of nicotine as much of the research into the potential harms of nicotine comes from studies in cells and animals where the doses used are often very high, leading to results that are controversial and difficult to extrapolate to humans

Tobacco alternatives are formulated without nicotine and without tobacco

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