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The mechanisms underlying an augmented GLP-1 response to intraduodenal glucose after Met (60 min) and Met (30 min) remain uncertain, but may reflect an effect of metformin on inhibiting glucose absorption in the upper small intestine, with consequent increased exposure of L cells to glucose more distally in the gut

Typically, this involves placing the used vial into a designated sharps container

10.3389/fmed.2021.630962 124 YiH.DuanY.SongR.ZhouY.CuiY.LiuC.et al (2023)