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Obesity is a leading global public health crisis

In line with these observations, the treatment of the murine syngeneic PCa and bladder cancer models with the JHU-083 inhibitor led to the reprogramming of the tumor-associated macrophages (TAMs) from an immunosuppressive to inflammatory state and increased TAM proliferation and glycolysis [99]

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Int J Clin Pharmacol Res 10:7579 Sanders YY, Liu H, Zhang X, Hecker L, Bernard K et al (2013) Histone modifications in senescence-associated resistance to apoptosis by oxidative stress

The existence of interactions between thiols and -lactam antibiotics, both in vitro and in vivo , has long been known