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Therefore, this study aims to (a) examine responses to the CRAFFT screening tool among Costa Rican secondary school students, (b) classify substance use risk into low, medium, and high categories based on internationally recommended CRAFFT thresholds and describe their prevalence, and (c) analyze the associations between CRAFFT risk levels and potential predictors, including sociodemographic factors, family history of SU, sexual activity under the influence of substances, and exposure to various types of violence (i.e., physical, psychological, and sexual)