doi: 10.1176/appi.ajp.2011.10101532
Our findings align with these previous studies, leading us to hypothesize that GSH levels are higher in the tumor tissues of chemotherapy-resistant breast cancer patients compared to chemotherapy-sensitive patients
Meanwhile, the results of Western blot assay showed that the protein expression levels of Cyclin A2 , Cyclin E2 , c-MYC , Cyclin D1 and CDK2 were significantly increased in the RRM2 overexpression group, and Cyclin D1 , Cyclin E1/E2 and Cyclin A2 are important regulators driving the cell cycle process, and their high expression is often associated with the acceleration of G1/S phase transition
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Furthermore, ELISA results confirmed that the use of the inhibitor MSAB prevented increases in the Fgf7 and Vegf concentrations in the supernatants of co-cultured hUCMSCs and DPCs (Fig