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The analysis found that trial participants who received retatrutide (Eli Lilly) an investigational triple agonist that activates the glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 (GLP-1), and glucagon receptors experienced the greatest weight loss reductions among the agents studied

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If you develop new tingling, numbness, or fatigue after starting retatrutide, do not attribute these symptoms to the drug alone before ruling out B12 deficiency

Because cardiovascular disease is the leading cause of death in people with diabetes, reducing these risks improves survival and quality of life